Kamsky's strategic depth was shown via moves like 13. a5, which in fact is aimed at undermining the center. Friedel had multiple chances to equalize or gain counterplay, but instead ended up choosing to play his opponent's game rather than his own. I identify move 21 as the key strategic decision point for Black, as he deliberately passes up unbalanced play on the queenside, where he has an advantage, in favor of attempting to shore up his kingside defenses. Black's subsequent awkward defensive contortions are eventually exploited by White, who ends up dominating the entire board.
The game is worth examining for its individual positional and tactical decisions, but what stands out are the strategic factors and the role psychology played, with Black evidently feeling the pressure of playing against his world-class opponent.